Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MDH1 | P40925 | 5/20 | 0.43 |
| ▸ | MDH2 | P40926 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933825 | 0.88 | KDM4E (0.48) | HDAC6ESR1KDM4EPOLBCA12 | |
| SCHEMBL7940256 | 0.86 | HSP90AA1 (0.52) | HDAC6ESR1KDM4EPOLBCA12 | |
| SCHEMBL7933737 | 0.85 | ESR1 (0.51) | HDAC6ESR1KDM4EPOLBCA12 | |
| SCHEMBL7943051 | 0.84 | HDAC6 (0.48) | HDAC6KDM4EPOLBMDH1MDH2 | |
| SCHEMBL7933567 | 0.81 | SERPINE1 (0.42) | ESR1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7944749 | 0.80 | ESR1 (0.52) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL7933960 | 0.79 | ESR1 (0.43) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL3810030 | 0.78 | POLB (0.52) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL7933761 | 0.77 | APP (0.52) | MDH1MDH2SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7941343 | 0.76 | SCN1A (0.40) | ESR1SMN1; SMN2LMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0861847-A2 | Stabilizer composition and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-02 | — | — | EP | disclosed |