Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942545 | 0.90 | ESR1 (0.41) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7933567 | 0.87 | SERPINE1 (0.42) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7942431 | 0.87 | HSPA5 (0.45) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7933964 | 0.86 | ESR1 (0.47) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7944749 | 0.86 | ESR1 (0.52) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7944996 | 0.85 | CYP3A4 (0.39) | ESR1LMNACYP2D6TSHRMAPK1 | |
| SCHEMBL3809056 | 0.79 | ALDH1A1 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9556848 | 0.79 | SERPINE1 (0.50) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7933735 | 0.79 | HDAC6 (0.47) | ESR1SERPINE1CA12CA1CA2 | |
| SCHEMBL11425542 | 0.79 | ESR1 (0.63) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0861847-A2 | Stabilizer composition and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-02 | — | — | EP | disclosed |