Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941344 | 0.90 | ESR1 (0.40) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7944998 | 0.89 | ESR1 (0.40) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7942531 | 0.87 | ESR1 (0.42) | ESR1 | |
| SCHEMBL7944750 | 0.86 | ESR1 (0.59) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7933777 | 0.86 | ESR1 (0.41) | ESR1 | |
| SCHEMBL7792421 | 0.83 | PLA2G2A (0.40) | ESR1CNR1CNR2 | |
| SCHEMBL7942462 | 0.83 | ESR1 (0.41) | ESR1 | |
| SCHEMBL7933770 | 0.81 | CNR2 (0.39) | CNR1CNR2 | |
| SCHEMBL7943054 | 0.81 | CNR2 (0.48) | ESR1CNR1CNR2 | |
| SCHEMBL7933568 | 0.80 | ESR1 (0.48) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |