Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL28186225 | 0.93 | ACP3 (0.42) | ACP3TSHRANPEPKMT2AMEN1 | |
| SCHEMBL31572025 | 0.83 | HPGD (0.44) | ACP3TSHRANPEPKMT2AMEN1 | |
| SCHEMBL27819571 | 0.81 | CA12 (0.54) | TSHRANPEPIDO1CYP1A2CYP2D6 | |
| SCHEMBL27552827 | 0.80 | KMT2A (0.56) | ACP3TSHRANPEPKMT2AMEN1 | |
| SCHEMBL10628324 | 0.79 | CYP19A1 (0.42) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2849816 | 0.76 | KMT2A (0.59) | TSHRANPEPKMT2AMEN1HTT | |
| Phosphoric Acid SCHEMBL28219527 | 0.74 | ANPEP (0.61) | ACP3ANPEPKMT2AMEN1THRB | |
| Phosphoric Acid SCHEMBL28219526 | 0.74 | ANPEP (0.61) | ACP3ANPEPKMT2AMEN1THRB | |
| SCHEMBL1377592 | 0.72 | KMT2A (0.55) | ACP3TSHRANPEPKMT2AMEN1 | |
| SCHEMBL28155502 | 0.72 | HPGD (0.51) | TSHRKMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107286190-A | The preparation of oxyl benzylamino phosphoric acid/phosphate derivatives of nucleosides and its medical usage | 刘沛 | 2017-10-24 | — | — | CN | claimed |
| CN-106459127-A | Nucleoside derivatives for the treatment of cancer | 艾登尼克斯药业有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106316966-A | Preparation method of medical intermediate N-(2-methylpyrazine)benzylamine phosphate compound | 董运勤 | 2017-01-11 | — | — | CN | claimed |
| CN-102532199-B | The structure of novel benzyl amido phosphate prodrug of nucleoside compound and synthesis | LIU PEI (CN) | 2015-08-05 | — | — | CN | claimed |
| CN-100361978-C | 2-pyrimidine oxy-N-aryl 7-nitrile or organic phosphate benzylamine compound, its production and use thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2008-01-16 | — | — | CN | claimed |
| CN-1746161-A | 2-2-pyrimidinyl oxy-N-aryl-7-itrile group or organic phosphate benzylamine compound, preparation method and its usage | SHANGHAI INST ORGANIC CHEM (CN) | 2006-03-15 | — | — | CN | claimed |
| CN-106188192-B | Nucleosides phosphoramidic acid/the phosphate derivatives and its medical usage of the amino-acid ester containing D- | 刘沛 | 2019-09-10 | — | — | CN | disclosed |
| CN-107286190-A | The preparation of oxyl benzylamino phosphoric acid/phosphate derivatives of nucleosides and its medical usage | 刘沛 | 2017-10-24 | — | — | CN | disclosed |
| CN-103980318-B | Nucleoside phosphorylase ester prodrugs containing substituted benzyl and its production and use | 刘沛 | 2017-08-25 | — | — | CN | disclosed |
| CN-106459127-A | Nucleoside derivatives for the treatment of cancer | 艾登尼克斯药业有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106316966-A | Preparation method of medical intermediate N-(2-methylpyrazine)benzylamine phosphate compound | 董运勤 | 2017-01-11 | — | — | CN | disclosed |
| CN-106188192-A | Nucleoside phosphoramidic acid phosphate derivatives containing D-amino-acid ester and medical usage thereof | 刘沛 | 2016-12-07 | — | — | CN | disclosed |
| CN-102532199-B | The structure of novel benzyl amido phosphate prodrug of nucleoside compound and synthesis | LIU PEI (CN) | 2015-08-05 | — | — | CN | disclosed |
| CN-100361978-C | 2-pyrimidine oxy-N-aryl 7-nitrile or organic phosphate benzylamine compound, its production and use thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2008-01-16 | — | — | CN | disclosed |
| CN-101001865-A | Purine nucleotide derivatives | LAURAS AS (NO) | 2007-07-18 | — | — | CN | disclosed |
| CN-1746161-A | 2-2-pyrimidinyl oxy-N-aryl-7-itrile group or organic phosphate benzylamine compound, preparation method and its usage | SHANGHAI INST ORGANIC CHEM (CN) | 2006-03-15 | — | — | CN | disclosed |
| CN-1746161-A | 2-2-pyrimidinyl oxy-N-aryl-7-itrile group or organic phosphate benzylamine compound, preparation method and its usage | SHANGHAI INST ORGANIC CHEM (CN) | 2006-03-15 | — | — | CN | disclosed |
| CN-1746161-A | 2-2-pyrimidinyl oxy-N-aryl-7-itrile group or organic phosphate benzylamine compound, preparation method and its usage | SHANGHAI INST ORGANIC CHEM (CN) | 2006-03-15 | — | — | CN | disclosed |
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |
| US-5190822-A | Drug delivery, stability | FUJI PHOTO FILM CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |