SCHEMBL1377592

SCHEMBL1377592

O=P(O)(O)NCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
HTT P42858 1/20 0.55
ACP3 P15309 3/20 0.52
IDO1 P14902 2/20 0.50
THRB P10828 1/20 0.50
ANPEP P15144 1/20 0.50
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
TSHR P16473 1/20 0.47
FDPS P14324 1/20 0.45
CA12 O43570 2/20 0.45
CA2 P00918 2/20 0.45
ADH1B P00325 1/20 0.45
ADH1C P00326 1/20 0.45
ADH1A P07327 1/20 0.45
ADH7 P40394 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
ALOX12 P18054 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10717268 0.83 KMT2A (0.52) KMT2AMEN1HTTACP3IDO1
SCHEMBL6686040 0.83 KMT2A (0.52) KMT2AMEN1HTTACP3IDO1
SCHEMBL3084524 0.79 KMT2A (0.49) KMT2AMEN1HTTACP3IDO1
Phosphoric Acid SCHEMBL28219526 0.79 ANPEP (0.61) KMT2AMEN1ACP3IDO1THRB
Phosphoric Acid SCHEMBL28219527 0.79 ANPEP (0.61) KMT2AMEN1ACP3IDO1THRB
SCHEMBL23884969 0.78 PLA2G1B (0.48) KMT2AHTTLMNACA12ALDH1A1
SCHEMBL6901813 0.78 CA12 (0.59) IDO1ANPEPLMNAMAPTTSHR
SCHEMBL27501482 0.78 CA2 (0.43) KMT2AMEN1HTTACP3ANPEP
SCHEMBL18266875 0.78 KMT2A (0.53) KMT2AMEN1HTTACP3IDO1
SCHEMBL6686042 0.77 ALOX12 (0.50) KMT2AMEN1HTTACP3IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4200309-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES ATEA Pharmaceuticals, Inc. (US) 2023-06-28 EP claimed
WO-2022040473-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2022-02-24 WO claimed
US-9682090-B2 Methods for treating and preventing prostate cancer bone metastases UNIVERSITY OF WASHINGTON (US) 2017-06-20 US claimed
US-20160136189-A1 METHODS FOR TREATING AND PREVENTING PROSTATE CANCER BONE METASTASES UNIVERSITY OF WASHINGTON (US) 2016-05-19 US claimed
US-20120108533-A1 NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) 2012-05-03 US claimed
WO-2010125200-A1 NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL ANGENTS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2010-11-04 WO claimed
EP-0929636-B1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME, PEPTIDE ALDEHYDE AND A SOURCE OF BORIC ACID PROCTER & GAMBLE (US) 2002-12-04 EP claimed
EP-0929639-B1 LIQUID DETERGENTS CONTAINING PROTEOLYTIC ENZYME, PEPTIDE ALDEHYDE AND CALCIUM IONS PROCTER & GAMBLE (US) 2002-11-13 EP claimed
US-20260085087-A1 CHEMICAL COMPOUND COMPRISING A TRIAZINE GROUP AND METHOD FOR PRODUCING SAME KUPRYUSHKIN MAXIM SERGEEVICH (RU) 2026-03-26 US disclosed
CN-118804917-A STAT modulators and uses thereof 瑞克鲁迪克斯制药股份有限公司 2024-10-18 CN disclosed
CN-114450607-B Polarizer and image display device 富士胶片株式会社 2024-09-27 CN disclosed
CN-114879298-B Polarizer and image display device 富士胶片株式会社 2023-11-14 CN disclosed
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2023-10-19 US disclosed
EP-4200309-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES ATEA Pharmaceuticals, Inc. (US) 2023-06-28 EP disclosed
EP-1765844-A2 PURINE NUCLEOTIDE DERIVATIVES Lauras AS (NO) 2007-03-28 EP disclosed
WO-2005123755-A2 PURINE NUCLEOTIDE DERIVATIVES LAURAS AS (NO) 2005-12-29 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
US-20030138432-A1 Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs DRUG INNOVATION & DESIGN, INC. 2003-07-24 US disclosed
EP-1255567-A1 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES Drug Innovation & Design, Inc. (US) 2002-11-13 EP disclosed
WO-2001036003-A2 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES DRUG INNOVATION & DESIGN, INC. (US) 2001-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085087-A1 CHEMICAL COMPOUND COMPRISING A TRIAZINE GROUP AND METHOD FOR PRODUCING SAME NSUN2, POLM, SSU72 KMT2A 2357/4885MEN1 4720/4885HTT 1612/4885
US-20030138432-A1 Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs PAICS, ABCB1, ABCG2 KMT2A 2336/4885MEN1 2448/4885HTT 2833/4885
US-20120108533-A1 NOVEL PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS PNP, TYMP, MTAP KMT2A 3176/4885MEN1 4664/4885HTT 4452/4885
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES NUDT1, PNP, ATIC KMT2A 3176/4885MEN1 933/4885HTT 1872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.