Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.38 |
| ▸ | NOS2 | P35228 | 5/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 4/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7927499 | 0.91 | NR3C1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7936751 | 0.91 | FNTA (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7939460 | 0.89 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7933752 | 0.88 | PSEN1 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7936786 | 0.84 | DAO (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7933783 | 0.83 | FNTA (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Hydrochloric Acid SCHEMBL7927511 | 0.80 | FNTA (0.45) | — | |
| SCHEMBL7927530 | 0.80 | BRS3 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7927492 | 0.77 | BRS3 (0.37) | NOS2SLC6A4PGRNOS1NOS3 | |
| SCHEMBL7939467 | 0.76 | PSEN1 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |