SCHEMBL7933905

SCHEMBL7933905

CC(C)(C)c1cc(CNCCO)c(O)c(C(C)(C)C)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.62
ALDH1A1 P00352 4/20 0.42
MAPK1 P28482 3/20 0.42
HTT P42858 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
GAA P10253 1/20 0.42
XBP1 P17861 1/20 0.42
NR5A2 O00482 1/20 0.42
NR5A1 Q13285 1/20 0.42
CYP2C19 P33261 7/20 0.40
HSPA5 P11021 2/20 0.40
CYP2C9 P11712 6/20 0.40
CYP1A2 P05177 4/20 0.40
CYP2D6 P10635 4/20 0.40
HIF1A Q16665 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 3/20 0.38
CYP3A4 P08684 2/20 0.38
HSP90AA1 P07900 1/20 0.37
SCN2A Q99250 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6053408 0.92 GSR (0.50) GSRALDH1A1MAPK1HTTNPSR1
SCHEMBL7943209 0.91 GSR (0.51) GSRALDH1A1MAPK1HTTNPSR1
SCHEMBL7940416 0.90 GSR (0.50) GSRALDH1A1MAPK1HTTNPSR1
SCHEMBL6053706 0.89 GSR (0.47) GSRALDH1A1MAPK1HTTNPSR1
SCHEMBL31043275 0.89 ALDH1A1 (0.47) GSRALDH1A1MAPK1HTTNPSR1
SCHEMBL11593073 0.88 GSR (0.46) GSRALDH1A1MAPK1HTTNPSR1
SCHEMBL24871017 0.86 GSR (0.45) GSRALDH1A1MAPK1HTTNPSR1
SCHEMBL28789635 0.86 GSR (0.45) GSRALDH1A1MAPK1HTTNPSR1
Hydrochloric Acid SCHEMBL27821211 0.85 GSR (0.47) GSRALDH1A1MAPK1HTTNPSR1
SCHEMBL7942924 0.84 GSR (0.62) GSRALDH1A1MAPK1HTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101928251-B Nitrogen bridged bisphenol functionalized imidazole and ionic iron (III) complex thereof UNIV SUZHOU 2013-06-19 CN disclosed
CN-101928251-A Nitrogen bridged bisphenol functionalized imidazole and ionic iron (III) complex thereof UNIV SUZHOU 2010-12-29 CN disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed