Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | F7 | P08709 | 2/20 | 0.34 |
| ▸ | F3 | P13726 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930427 | 0.92 | GHSR (0.68) | GHSRAGTR1XIAPDRD2DRD4 | |
| SCHEMBL7932746 | 0.92 | GHSR (0.48) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL7932751 | 0.92 | GHSR (0.48) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL7933945 | 0.91 | GHSR (0.48) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL7933939 | 0.91 | GHSR (0.48) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL7923950 | 0.90 | GHSR (0.47) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL7923948 | 0.90 | GHSR (0.47) | GHSRAGTR1XIAPF7F3 | |
| SCHEMBL7792083 | 0.87 | GHSR (0.64) | GHSRAGTR1XIAPDRD2DRD4 | |
| SCHEMBL7791991 | 0.85 | GHSR (0.58) | GHSRAGTR1XIAPDRD2DRD4 | |
| SCHEMBL7786011 | 0.85 | GHSR (0.57) | GHSRAGTR1XIAPF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211174-B1 | OSTEOPOROSIS; MILK PRODUCTION AND CARCASS QUALITY IN LIVESTOCK; SHORT STATURE; METABOLIC DISORDERS | MERCK & CO., INC. | 2001-04-03 | — | — | US | disclosed |