Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 7/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937286 | 0.95 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BDRD2HTR6 | |
| Hydrochloric Acid SCHEMBL7934777 | 0.91 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BDRD2HTR6 | |
| SCHEMBL7924486 | 0.90 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL7931374 | 0.90 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL7934761 | 0.89 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL7924505 | 0.89 | ADRA1D (0.55) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7937265 | 0.88 | ADRA1D (0.46) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7924576 | 0.88 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL7933294 | 0.88 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL7924599 | 0.88 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242449-B1 | TREATING PROSTATIC HYPERTROPHY, URINATION DISORDERS ASSOCIATED WITH PROSTATIC HYPERTROPHY, MALE PATTERN ALOPECIA, OR ACNE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0997457-A1 | 3-BENZOYLINDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-03 | — | — | EP | disclosed |