Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 6/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937279 | 0.94 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7934780 | 0.90 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7924491 | 0.89 | ADRA1D (0.53) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7931378 | 0.89 | ADRA1D (0.52) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7924512 | 0.89 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BKMT2A | |
| Hydrochloric Acid SCHEMBL7924578 | 0.88 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7933296 | 0.88 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7933279 | 0.87 | ADRA1D (0.52) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7924592 | 0.87 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BDRD2MEN1 | |
| Hydrochloric Acid SCHEMBL7937268 | 0.87 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BSRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242449-B1 | TREATING PROSTATIC HYPERTROPHY, URINATION DISORDERS ASSOCIATED WITH PROSTATIC HYPERTROPHY, MALE PATTERN ALOPECIA, OR ACNE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0997457-A1 | 3-BENZOYLINDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-03 | — | — | EP | disclosed |