Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194803 | 0.90 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL11687302 | 0.87 | TSHR (0.55) | TSHRIDO1AGXTALDH1A1CA1 | |
| Bromide SCHEMBL11675628 | 0.85 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 | |
| Carbon Monoxide SCHEMBL11680342 | 0.81 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL77609 | 0.81 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL9330479 | 0.81 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL383496 | 0.81 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL9052472 | 0.81 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL6035596 | 0.81 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL18650069 | 0.81 | TSHR (0.43) | TSHRIDO1AGXTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091508-B2 | Fosaprepitant phosphate intermediate and preparation method therefor | SHANGHAI AOBO PHARMTECH, INC., LTD. (CN) | 2021-08-17 | — | — | US | disclosed |
| EP-3456726-B1 | FOSAPREPITANT PHOSPHATE INTERMEDIATE AND PREPARATION METHOD THEREFOR | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2020-12-02 | — | — | EP | disclosed |
| US-20190144477-A1 | FOSAPREPITANT PHOSPHATE INTERMEDIATE AND PREPARATION METHOD THEREFOR | SHANGHAI AOBO PHARMTECH, INC., LTD. (CN) | 2019-05-16 | — | — | US | disclosed |
| EP-3456726-A1 | FOSAPREPITANT PHOSPHATE INTERMEDIATE AND PREPARATION METHOD THEREFOR | Zhejiang Huahai Pharmaceutical Co., Ltd (CN) | 2019-03-20 | — | — | EP | disclosed |
| US-6187890-B1 | CROSSLINK BY REACTION OF ALIPHATICALLY UNSATURATED GROUPS WITH SI-BONDED HYDROGEN (HYDROSILYLATION) IN THE PRESENCE OF A CATALYST, TYPICALLY A PLATINUM COMPOUND | WACKER-CHEMIE GMBH (DE) | 2001-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091508-B2 | Fosaprepitant phosphate intermediate and preparation method therefor | VIPR1, VIP, CYP4A11 | TSHR 2514/4885IDO1 1157/4885AGXT 2014/4885 |
| US-20190144477-A1 | FOSAPREPITANT PHOSPHATE INTERMEDIATE AND PREPARATION METHOD THEREFOR | VIPR1, VIP, CYP4A11 | TSHR 2514/4885IDO1 1157/4885AGXT 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.