Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77609 | 0.95 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL194803 | 0.85 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL11687302 | 0.83 | TSHR (0.55) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL7934188 | 0.81 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 | |
| Bromide SCHEMBL11675628 | 0.81 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL17171596 | 0.80 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL28546168 | 0.78 | TSHR (0.44) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL1117737 | 0.78 | TSHR (0.55) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL9052472 | 0.77 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL383496 | 0.77 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393157-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | CHIRON AS (NO) | 2023-12-07 | — | — | US | claimed |
| EP-4214216-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | Chiron AS (NO) | 2023-07-26 | — | — | EP | claimed |
| WO-2022058192-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | CHIRON AS (NO) | 2022-03-24 | — | — | WO | claimed |
| EP-3971192-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | Chiron AS (NO) | 2022-03-23 | — | — | EP | claimed |
| US-20230393157-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | CHIRON AS (NO) | 2023-12-07 | — | — | US | disclosed |
| EP-4214216-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | Chiron AS (NO) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022058192-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | CHIRON AS (NO) | 2022-03-24 | — | — | WO | disclosed |
| EP-3971192-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | Chiron AS (NO) | 2022-03-23 | — | — | EP | disclosed |
| CN-101863923-B | Novel inhibitors of chymase | JANSSEN PHARMACEUTICA NV | 2013-04-24 | — | — | CN | disclosed |
| CN-1495189-B | Preparation method of phosphite ester and transition metal complex | SALTIGO GMBH | 2012-07-11 | — | — | CN | disclosed |
| CN-101863923-A | New inhibitors of chymase | JANSSEN PHARMACEUTICA NV | 2010-10-20 | — | — | CN | disclosed |
| CN-1934120-B | Novel chymase inhibitors | JANSSEN PHARMACEUTICA NV | 2010-05-26 | — | — | CN | disclosed |
| EP-0358985-A1 | Method of transhalogenating a halophosphorus compound with fluoride | ETHYL CORPORATION (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4910324-A | Using a metal or ammonium fluoride | ETHYL CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0357048-A2 | Process for transhalogenating a halophosphorus compound with hydrogen fluoride | ALBEMARLE CORPORATION (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0353598-A2 | Transhalogenation of halophosphorus compounds | ETHYL CORPORATION (US) | 1990-02-07 | — | — | EP | disclosed |
| EP-0312790-A2 | Process for transhalogenating a halophosphorus compound with fluoride | ETHYL CORPORATION (US) | 1989-04-26 | — | — | EP | disclosed |
| US-4242479-A | CATALYST OF ALUMINUM TRIHALIDE, ORGANOSILOXANE COMPOUND OR ETHER, MAGNESIUM ALCOHOLATE, TITANIUM-HALOGEN AND ORGANOALUMINUM COMPOUNDS | SHOWA YUKA KABUSHIKI KAISHA (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4180636-A | MAGNESIUM HALIDE, TITANIUM COMPOUND ELECTRON DONOR COMPOUND, TRIALKYL ALUMINUM CATALYST | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1979-12-25 | — | — | US | disclosed |
| US-4000239-A | PROCESS FOR SPINNING NAPHTHALATE POLYESTER FIBERS | TEIJIN LIMITED (JA) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230393157-A1 | PHOSPHATIDYLALKANOL HOMOLOGUES HAVING LABELLED MOIETIES | PHOSPHO1, SGMS2, SGMS1 | TSHR 4269/4885IDO1 4036/4885AGXT 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.