Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | DPP4 | P27487 | 3/20 | 0.50 |
| ▸ | FAP | Q12884 | 2/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | TPH1 | P17752 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672925 | 1.00 | GRB2 (0.57) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL12188586 | 1.00 | GRB2 (0.57) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL19143516 | 0.88 | GRB2 (0.55) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL43862 | 0.86 | GRB2 (0.76) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL12323865 | 0.86 | GRB2 (0.57) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL148122 | 0.86 | GRB2 (0.76) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL43861 | 0.86 | GRB2 (0.76) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL2738531 | 0.86 | GRB2 (0.57) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL16501752 | 0.85 | GRB2 (0.53) | GRB2PTPN1DPP4FAPDPP8 | |
| SCHEMBL14288393 | 0.85 | GRB2 (0.53) | GRB2PTPN1DPP4FAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814444-B2 | Cyclic polypeptides for PCSK9 inhibition | RA PHARMACEUTICALS, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| WO-2010016944-A2 | ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE (GIP) MODIFIED AT N-TERMINAL | IPSEN PHARMA S.A.S. (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010016936-A1 | PHARMACEUTICAL COMPOSITIONS OF ANALOGUES OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE | IPSEN PHARMA S.A.S. (FR) | 2010-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814444-B2 | Cyclic polypeptides for PCSK9 inhibition | PCSK9, LDLR, PCSK7 | GRB2 1230/4885PTPN1 682/4885DPP4 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.