Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 14/20 | 0.76 |
| ▸ | PTGER2 | P43116 | 13/20 | 0.76 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.76 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.76 |
| ▸ | PTGER4 | P35408 | 11/20 | 0.59 |
| ▸ | PTGFR | P43088 | 3/20 | 0.59 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.57 |
| ▸ | PTGIR | P43119 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7934285 | 1.00 | PTGER3 (0.76) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL7929810 | 0.86 | PTGER3 (1.00) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL7929816 | 0.86 | PTGER3 (1.00) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL157606 | 0.83 | PTGER3 (0.73) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL3214322 | 0.76 | PTGER3 (0.63) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL1150939 | 0.76 | PTGER3 (0.63) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL309761 | 0.76 | PTGER3 (0.63) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL9338278 | 0.76 | MAOB (0.46) | PTGER3PTGER2PTGDRTBXA2R | |
| SCHEMBL28904481 | 0.76 | PTGER3 (0.56) | PTGER3PTGER2PTGDRTBXA2RPTGER4 | |
| SCHEMBL9338285 | 0.76 | MAOB (0.46) | PTGER3PTGER2PTGDRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242493-B1 | PROSTAGLANDIN INHIBITORS; ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-06-05 | — | — | US | disclosed |