Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ACP1 | P24666 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849464 | 0.95 | ALDH1A1 (0.66) | ALDH1A1HPGDSMN1; SMN2LMNAMEN1 | |
| SCHEMBL15480445 | 0.94 | ALDH1A1 (0.67) | ALDH1A1HPGDNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL15480448 | 0.94 | ALDH1A1 (0.67) | ALDH1A1HPGDNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL15480450 | 0.94 | ALDH1A1 (0.67) | ALDH1A1HPGDNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL15480447 | 0.94 | ALDH1A1 (0.67) | ALDH1A1HPGDNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL15480444 | 0.92 | ALDH1A1 (0.68) | ALDH1A1HPGDNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL6252743 | 0.89 | MEN1 (0.61) | ALDH1A1HPGDSMN1; SMN2HSD17B10LMNA | |
| SCHEMBL8232990 | 0.88 | ALDH1A1 (0.60) | ALDH1A1HPGDNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL17817590 | 0.86 | ADORA2A (0.64) | ALDH1A1HPGDNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL7142997 | 0.86 | ADORA2A (0.64) | ALDH1A1HPGDNPSR1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028193-A1 | COMPOUNDS INCLUDING PIMELIC ACID DERIVATIVES AS HDAC INHIBITORS | REPLIGEN CORPORATION (US) | 2010-03-11 | — | — | WO | disclosed |