Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22607471 | 0.99 | NPC1 (0.36) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL22607477 | 0.86 | NPC1 (0.41) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL7102011 | 0.85 | NPC1 (0.35) | NPC1RAB9APNMT | |
| SCHEMBL7106532 | 0.85 | NPC1 (0.35) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL22607491 | 0.84 | NPC1 (0.34) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL7106551 | 0.82 | NPC1 (0.38) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL7107707 | 0.82 | PNMT (0.33) | NPC1RAB9APNMT | |
| SCHEMBL1081333 | 0.82 | NPC1 (0.39) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL7943311 | 0.82 | KDM4E (0.35) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6908139 | 0.81 | NPC1 (0.39) | NPC1RAB9APNMTHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316558-B1 | POLYMERIZING OLEFIN USING CATALYST COMPRISING TRANSITION METAL COMPOUND, COMPOUND CAPABLE OF A REACTING WITH TRANSITION METAL COMPOUND TO FORM A CATIONIC TRANSITION METAL COMPOUND, ORGANOMETALLIC TO FORM POLYOLEFIN | TOSOH CORPORATION (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-0786466-A1 | Transition metal compound, olefin polymerization catalyst comprising the compound, and process for production of olefin polymer | Tosoh Corporation (JP) | 1997-07-30 | — | — | EP | disclosed |