Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106984 | 0.86 | NPC1 (0.34) | NPC1RAB9AHTR7HTR2BPNMT | |
| SCHEMBL7107794 | 0.84 | NPC1 (0.33) | NPC1RAB9AHTR7HTR2BPNMT | |
| SCHEMBL7106058 | 0.83 | NPC1 (0.32) | NPC1RAB9AHTR7HTR2BPNMT | |
| SCHEMBL7941175 | 0.83 | PNMT (0.33) | NPC1RAB9AHTR7HTR2BPNMT | |
| SCHEMBL7104537 | 0.83 | NPC1 (0.32) | NPC1RAB9AHTR7HTR2BPNMT | |
| SCHEMBL7101060 | 0.82 | NPC1 (0.32) | NPC1RAB9AHTR7HTR2B | |
| SCHEMBL7940992 | 0.81 | PNMT (0.32) | NPC1RAB9APNMT | |
| SCHEMBL7101948 | 0.81 | PNMT (0.32) | NPC1RAB9APNMT | |
| SCHEMBL7103489 | 0.81 | PNMT (0.32) | NPC1RAB9APNMT | |
| SCHEMBL7943321 | 0.81 | PNMT (0.31) | NPC1RAB9APNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316558-B1 | POLYMERIZING OLEFIN USING CATALYST COMPRISING TRANSITION METAL COMPOUND, COMPOUND CAPABLE OF A REACTING WITH TRANSITION METAL COMPOUND TO FORM A CATIONIC TRANSITION METAL COMPOUND, ORGANOMETALLIC TO FORM POLYOLEFIN | TOSOH CORPORATION (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-0786466-A1 | Transition metal compound, olefin polymerization catalyst comprising the compound, and process for production of olefin polymer | Tosoh Corporation (JP) | 1997-07-30 | — | — | EP | disclosed |