Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27346955 | 0.73 | EPHX2 (0.39) | EPHX2KMT2A | |
| SCHEMBL8731825 | 0.71 | EPHX2 (0.54) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL17710514 | 0.71 | EPHX2 (0.36) | EPHX2KMT2AGAACXCR3 | |
| SCHEMBL8342119 | 0.70 | EPHX2 (0.44) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL6154914 | 0.70 | EPHX2 (0.52) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL9754167 | 0.69 | EPHX2 (0.63) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL1694528 | 0.69 | EPHX2 (0.63) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL3909801 | 0.69 | EPHX2 (0.63) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL6314315 | 0.69 | EPHX2 (0.63) | EPHX2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL12832525 | 0.68 | EPHX2 (0.51) | EPHX2MEN1HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242198-B1 | ADMINISTERING GUANIDINE COMPOUND | CAMBRIDGE NEUROSCIENCE, INC. | 2001-06-05 | — | — | US | disclosed |