SCHEMBL7934772

SCHEMBL7934772

C=CCOc1ccccc1C(=C)C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.59
TSHR P16473 3/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MAPK1 P28482 1/20 0.50
ADRB2 P07550 2/20 0.47
ADRB1 P08588 2/20 0.47
ADRB3 P13945 1/20 0.47
LMNA P02545 2/20 0.46
SLC22A1 O15245 1/20 0.46
CYP1A2 P05177 1/20 0.46
HTR1A P08908 1/20 0.46
CYP2D6 P10635 1/20 0.46
HTR2A P28223 1/20 0.46
SLC6A4 P31645 1/20 0.46
ADRA1A P35348 1/20 0.46
CYP3A4 P08684 2/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 4/20 0.43
GAA P10253 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1319409 0.84 LIG1 (0.67) LIG1TSHRHPGDHSD17B10MAPK1
SCHEMBL21616035 0.81 LIG1 (0.55) LIG1TSHRHPGDHSD17B10MAPK1
Acetic Acid SCHEMBL28195889 0.80 LIG1 (0.61) LIG1TSHRHPGDHSD17B10MAPK1
SCHEMBL7711829 0.80 MAPT (0.43) LIG1TSHRHPGDHSD17B10MAPK1
SCHEMBL9696302 0.80 LIG1 (0.71) LIG1TSHRHPGDHSD17B10MAPK1
SCHEMBL4952648 0.79 HCRTR1 (0.54) HPGDHSD17B10MAPK1LMNAKDM4E
SCHEMBL9374215 0.79 ALDH1A1 (0.44) LIG1TSHRHPGDHSD17B10LMNA
SCHEMBL9474674 0.79 LIG1 (0.59) LIG1TSHRHPGDHSD17B10MAPK1
SCHEMBL40310 0.79 LIG1 (0.69) LIG1TSHRHPGDHSD17B10MAPK1
SCHEMBL29519569 0.79 LIG1 (0.69) LIG1TSHRHPGDHSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277925-B1 COMPRISING A CURABLE POLYMER, AN ORGANIC PEROXIDE INITIATOR, AND AN ALLYL COMPOUND AS SCORCH RETARDER HERCULES INCORPORATED 2001-08-21 US disclosed
US-4298720-A HEAT RESISTANT MOLDING MATERIALS AND VULCANIZATION ACCELERATORS MITSUI TOATSU CHEMICALS INCORPORATED (JP) 1981-11-03 US disclosed