Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 20/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350022 | 0.82 | GRIA2 (0.57) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2937864 | 0.77 | CA1 (0.59) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL3349457 | 0.75 | GRIA2 (0.57) | GRIA2CYP1A2 | |
| SCHEMBL10090476 | 0.74 | GRIA2 (0.68) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL8213103 | 0.74 | GRIA2 (0.68) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL957414 | 0.73 | GRIA2 (0.54) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL8158583 | 0.72 | GRIA2 (0.59) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL585486 | 0.72 | GRIA2 (0.59) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL957572 | 0.72 | GRIA2 (0.59) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2935780 | 0.72 | GRIA2 (0.59) | GRIA2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066658-A1 | COMPOUNDS WHICH POTENTIATE THE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2010-06-17 | — | — | WO | disclosed |