SCHEMBL3349457

SCHEMBL3349457

CC(C)S(=O)(=O)N[C@H]1Cc2ccc(N3CCCC3=O)cc2C1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 18/20 0.57
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23519752 0.77 CYP3A4 (0.50) CYP1A2
SCHEMBL7934788 0.75 GRIA2 (0.50) GRIA2CYP1A2
SCHEMBL13565882 0.75 GRIA2 (0.42) GRIA2
SCHEMBL17090177 0.75 GRIA2 (0.42) GRIA2
SCHEMBL10116121 0.74 SMN1; SMN2 (0.44)
SCHEMBL10114937 0.74 KMT2A (0.55) GRIA2
SCHEMBL13204413 0.74 KMT2A (0.55) GRIA2
SCHEMBL25086366 0.74 ALDH1A1 (0.43) CYP1A2
SCHEMBL2934244 0.73 GRIA2 (1.00) GRIA2CYP1A2
SCHEMBL10090476 0.73 GRIA2 (0.68) GRIA2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010066658-A1 COMPOUNDS WHICH POTENTIATE THE AMPA RECEPTOR AND USES THEREOF IN MEDICINE GLAXO GROUP LIMITED (GB) 2010-06-17 WO disclosed
WO-2010066658-A1 COMPOUNDS WHICH POTENTIATE THE AMPA RECEPTOR AND USES THEREOF IN MEDICINE GLAXO GROUP LIMITED (GB) 2010-06-17 WO disclosed