Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263544 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4ERAB9ANPC1LMNA | |
| SCHEMBL3263543 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4ERAB9ANPC1LMNA | |
| SCHEMBL3228556 | 0.80 | ALDH1A1 (0.82) | NAMPTALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL3228566 | 0.80 | ALDH1A1 (0.82) | NAMPTALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL25722340 | 0.80 | HDAC1 (0.77) | HDAC1NAMPTKDM4ERAB9ANPC1 | |
| SCHEMBL21232419 | 0.80 | HDAC4 (0.72) | HDAC1NAMPTRAB9ANPC1HDAC2 | |
| SCHEMBL16016614 | 0.75 | HDAC4 (0.73) | HDAC1HDAC2HDAC3LMNAHDAC4 | |
| SCHEMBL28410554 | 0.74 | HDAC1 (1.00) | HDAC1NAMPTRAB9ANPC1HDAC2 | |
| SCHEMBL17667093 | 0.74 | ALDH1A1 (1.00) | NAMPTALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL14164232 | 0.74 | ALDH1A1 (0.71) | ALDH1A1KDM4ERAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028193-A1 | COMPOUNDS INCLUDING PIMELIC ACID DERIVATIVES AS HDAC INHIBITORS | REPLIGEN CORPORATION (US) | 2010-03-11 | — | — | WO | disclosed |