Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935162 | 1.00 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EMEN1PSMD14 | |
| SCHEMBL7366261 | 0.94 | KDM4E (0.44) | ITGB3ITGA2BKDM4EMEN1PSMD14 | |
| SCHEMBL7366256 | 0.94 | KDM4E (0.44) | ITGB3ITGA2BKDM4EMEN1PSMD14 | |
| SCHEMBL7449531 | 0.89 | HSD17B10 (0.55) | ITGB3ITGA2BKDM4EKMT2ACYP3A4 | |
| SCHEMBL7449519 | 0.89 | HSD17B10 (0.55) | ITGB3ITGA2BKDM4EKMT2ACYP3A4 | |
| SCHEMBL7368990 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BMMP2 | |
| SCHEMBL7368980 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BMMP2 | |
| SCHEMBL7368598 | 0.84 | KDM4E (0.52) | KDM4EKMT2ACYP3A4CYP2C9HPGD | |
| SCHEMBL7368594 | 0.84 | KDM4E (0.52) | KDM4EKMT2ACYP3A4CYP2C9HPGD | |
| SCHEMBL7448765 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2BMMP2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |