Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.74 |
| ▸ | PGR | P06401 | 1/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | HTR2B | P41595 | 1/20 | 0.74 |
| ▸ | MC3R | P41968 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.74 |
| ▸ | PTGFR | P43088 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935151 | 1.00 | PDE4D (0.74) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7935149 | 1.00 | PDE4D (0.74) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7935147 | 1.00 | PDE4D (0.74) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL16487703 | 0.97 | PDE4D (0.75) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7617428 | 0.90 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7617422 | 0.90 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7617431 | 0.90 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL8901969 | 0.88 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL8901976 | 0.88 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL19845838 | 0.87 | PDE4D (0.59) | PDE4DPGRADORA3ADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242485-B1 | ADMINISTERING PROSTANOIC ACID DERIVATIVE TO TREAT VISION, KIDNEY, CARDIOVASCULAR AND BRAIN DISORDERS; HYPOTENSIVE AND ANTIASTHMATIC AGENTS | R-TECH UENO (JP) | 2001-06-05 | — | — | US | disclosed |