Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.75 |
| ▸ | PGR | P06401 | 1/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.75 |
| ▸ | HTR2B | P41595 | 1/20 | 0.75 |
| ▸ | MC3R | P41968 | 1/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.75 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.75 |
| ▸ | PTGFR | P43088 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935149 | 0.97 | PDE4D (0.74) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7935147 | 0.97 | PDE4D (0.74) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7935153 | 0.97 | PDE4D (0.74) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL7935151 | 0.97 | PDE4D (0.74) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL8903423 | 0.90 | PDE4D (0.84) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL8903428 | 0.90 | PDE4D (0.84) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL18388401 | 0.90 | PDE4D (0.84) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL18656728 | 0.89 | PDE4D (0.60) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL19851568 | 0.89 | PDE4D (0.60) | PDE4DPGRADORA3ADRA2CSLC6A2 | |
| SCHEMBL8901969 | 0.89 | PDE4D (0.82) | PDE4DPGRADORA3ADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353055-B2 | Method for the purification of prostaglandins | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2016-05-31 | — | — | US | disclosed |
| US-20150126764-A1 | METHOD FOR THE PURIFICATION OF PROSTAGLANDINS | MACFARLAN SMITH LIMITED (GB) | 2015-05-07 | — | — | US | disclosed |
| US-8957240-B2 | Method for the purification of prostaglandins | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2015-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126764-A1 | METHOD FOR THE PURIFICATION OF PROSTAGLANDINS | PTGES, PTGES2, PTGS2 | PDE4D 2575/4885PGR 566/4885ADORA3 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.