Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 9/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.61 |
| ▸ | HCN1 | O60741 | 1/20 | 0.61 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18840868 | 0.89 | CCR3 (1.00) | CCR3TP53HCN1HCN4GAA | |
| SCHEMBL7934793 | 0.85 | CCR3 (0.82) | CCR3 | |
| SCHEMBL7938472 | 0.84 | CCR3 (0.59) | CCR3TP53SLC1A2MEN1KMT2A | |
| SCHEMBL7932702 | 0.83 | MEN1 (0.70) | CCR3TP53SLC1A2MEN1KMT2A | |
| SCHEMBL7932599 | 0.81 | CCR3 (0.71) | CCR3SLC1A2HCN1HCN4MEN1 | |
| SCHEMBL7938483 | 0.80 | GAA (0.76) | CCR3GAAMEN1KMT2AMAPT | |
| SCHEMBL18840915 | 0.76 | CCR3 (1.00) | CCR3 | |
| SCHEMBL25431561 | 0.76 | SLC1A2 (1.00) | CCR3TP53SLC1A2GAAMEN1 | |
| SCHEMBL31367937 | 0.76 | SLC1A2 (1.00) | CCR3TP53SLC1A2GAAMEN1 | |
| SCHEMBL30482357 | 0.76 | SLC1A2 (1.00) | CCR3TP53SLC1A2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6235732-B1 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |