Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | CASR | P41180 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 2/20 | 0.51 |
| ▸ | HTR1B | P28222 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932702 | 0.84 | MEN1 (0.70) | CCR3MEN1KMT2ASLC1A2TP53 | |
| SCHEMBL7935240 | 0.84 | CCR3 (0.80) | CCR3MEN1KMT2ASLC1A2TP53 | |
| SCHEMBL7936481 | 0.83 | CCR3 (0.77) | CCR3 | |
| SCHEMBL7938443 | 0.78 | CCR3 (0.72) | CCR3MEN1KMT2ASLC1A2 | |
| SCHEMBL444179 | 0.77 | CASR (0.74) | CCR3MEN1KMT2ACASRLMNA | |
| SCHEMBL30482318 | 0.77 | SLC1A2 (0.63) | CCR3MEN1KMT2ASLC1A2LMNA | |
| SCHEMBL18840868 | 0.74 | CCR3 (1.00) | CCR3MEN1KMT2ATP53 | |
| SCHEMBL7934825 | 0.74 | GAA (0.64) | CCR3TP53 | |
| SCHEMBL18840821 | 0.73 | CCR3 (1.00) | CCR3MEN1KMT2ALMNATP53 | |
| SCHEMBL18840859 | 0.72 | CCR3 (1.00) | CCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235732-B1 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |