Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728536 | 0.91 | MAPT (0.41) | HPRT1ALDH1A1HSD17B10TSHRCYP2A6 | |
| SCHEMBL2965691 | 0.72 | DHFR (0.38) | ALDH1A1HSD17B10TSHRCYP2A6CYP1A2 | |
| SCHEMBL2959981 | 0.72 | DHFR (0.35) | ALDH1A1CYP2A6CYP1A2MEN1CYP2D6 | |
| Methane SCHEMBL28077352 | 0.72 | HPRT1 (0.93) | HPRT1ALDH1A1HSD17B10TSHRCYP2A6 | |
| Chrysene SCHEMBL28385926 | 0.72 | HPRT1 (0.93) | HPRT1ALDH1A1HSD17B10TSHRCYP2A6 | |
| SCHEMBL2969925 | 0.70 | CYP2D6 (0.31) | ALDH1A1HPGDMEN1CYP2D6CYP2C19 | |
| SCHEMBL7040527 | 0.70 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL25510 | 0.69 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10TSHRCYP2A6 | |
| Chrysene SCHEMBL27115 | 0.69 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10TSHRCYP2A6 | |
| SCHEMBL31177955 | 0.69 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10TSHRCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329486-B1 | PHYSICAL PROPERTIES | THE DOW CHEMICAL COMPANY | 2001-12-11 | — | — | US | disclosed |
| US-6323294-B1 | CONTACTING C.SUB.2-100,000 OLEFIN/S UNDER POLYMERIZATION CONDITIONS WITH CATALYST SYSTEM COMPRISING METAL COMPLEX AND ACTIVATING COCATALYST OR REACTION PRODUCT OF METAL COMPLEX AND COCATALYST TO FORM ADDITION POLYMER | THE DOW CHEMICAL COMPANY | 2001-11-27 | — | — | US | disclosed |