Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 14/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18840926 | 0.92 | CCR3 (1.00) | CCR3CYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL18840933 | 0.92 | CCR3 (1.00) | CCR3TP53MAPTTHRBMEN1 | |
| SCHEMBL7932702 | 0.86 | MEN1 (0.70) | CCR3CYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL7986617 | 0.86 | CCR3 (0.71) | CCR3 | |
| SCHEMBL7934845 | 0.82 | CCR3 (0.70) | CCR3 | |
| SCHEMBL7936440 | 0.80 | CCR3 (0.75) | CCR3TP53MAPTTHRBMEN1 | |
| SCHEMBL18840917 | 0.80 | CCR3 (1.00) | CCR3 | |
| SCHEMBL7925833 | 0.80 | CCR3 (0.86) | CCR3 | |
| SCHEMBL18840871 | 0.78 | CCR3 (1.00) | CCR3TP53MAPT | |
| SCHEMBL7987289 | 0.78 | CCR3 (0.79) | CCR3TP53MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6235732-B1 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |