SCHEMBL7935672

SCHEMBL7935672

C[C@@H](CCl)OCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
IDO1 P14902 1/20 0.41
SLC1A3 P43003 2/20 0.41
SLC1A2 P43004 2/20 0.41
SLC1A1 P43005 2/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 2/20 0.40
AGXT P21549 1/20 0.40
RCE1 Q9Y256 1/20 0.40
ALDH1A1 P00352 2/20 0.39
SLC6A2 P23975 2/20 0.39
TAAR1 Q96RJ0 2/20 0.39
MAOA P21397 1/20 0.39
SLC6A4 P31645 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9576999 1.00 TSHR (0.44) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL6806227 0.84 TSHR (0.41) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL20995917 0.83 TSHR (0.48) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL2554445 0.83 TAAR1 (0.52) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL92279 0.81 TSHR (0.46) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL12549624 0.81 TSHR (0.46) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL14310474 0.81 TSHR (0.46) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL647501 0.79 TRPA1 (0.48) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL18579815 0.79 IDO1 (0.46) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL7864015 0.79 IDO1 (0.46) TSHRIDO1SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6306828-B1 ENTERIC OR PARENTAL SOLUTION OF ALPHA-AND/OR BETA-D-GLUCOPYRANOSYL C2-C20 ALKANOATE; WOUND HEALING AGENTS; DIETETICS; TRAUMAS, METABOLIC DISORDERS BAXTER INTERNATIONAL, INC. 2001-10-23 US disclosed
EP-0736256-B1 Enantiomerically-enhanced nutritional energy substrates BAXTER INT (US) 1999-06-23 EP disclosed
EP-0736256-A1 Enantiomerically-enhanced nutritional energy substrates CLINTEC NUTRITION COMPANY (US) 1996-10-09 EP disclosed