SCHEMBL7935675

SCHEMBL7935675

CC1=Cc2c(-c3ccccc3)cccc2C1[Hf](Cl)(Cl)(C1C(C)=Cc2c(-c3ccccc3)cccc21)=[Si](C)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7935413 0.88 USP30 (0.31) USP30CYP2A6
SCHEMBL1201261 0.88 CYP2A6 (0.33) CYP2A6
SCHEMBL7939138 0.85
SCHEMBL6056248 0.82
SCHEMBL7935722 0.81
SCHEMBL219026 0.80 BRD4 (0.32) USP30CYP2A6
SCHEMBL6056149 0.79 USP30 (0.32) USP30
SCHEMBL17387117 0.79 HTR2B (0.32) USP30
SCHEMBL7938857 0.78 KDM4E (0.30)
SCHEMBL7926987 0.77 BRD4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed