SCHEMBL7938857

SCHEMBL7938857

CC1=Cc2c(-c3ccccc3)cccc2C1[Hf](Cl)(Cl)(C1C(C)=Cc2c(-c3ccccc3)cccc21)=[Ge](c1ccccc1)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7936107 0.88 GABRP (0.30)
SCHEMBL7926987 0.86 BRD4 (0.31)
SCHEMBL7926735 0.85 ALDH1A1 (0.32) ALDH1A1
SCHEMBL219026 0.81 BRD4 (0.32)
SCHEMBL7933055 0.80 LMNA (0.33) LMNA
Hydrochloric Acid SCHEMBL6438059 0.79 BRD4 (0.33)
SCHEMBL7935413 0.79 USP30 (0.31)
SCHEMBL217396 0.78 HTR2B (0.31)
SCHEMBL217237 0.78 BRD4 (0.31)
SCHEMBL1201261 0.78 CYP2A6 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184402-B1 RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES CHISSO CORPORATION (JP) 2001-02-06 US disclosed