Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938558 | 0.85 | ATM (0.44) | SMN1; SMN2 | |
| SCHEMBL6295368 | 0.84 | PDE10A (0.33) | PDE10APDE2ASMN1; SMN2 | |
| SCHEMBL7936558 | 0.83 | HPGD (0.41) | SMN1; SMN2 | |
| SCHEMBL9857238 | 0.80 | KDM4E (0.36) | — | |
| SCHEMBL6974446 | 0.80 | SCN9A (0.32) | SCN9A | |
| SCHEMBL3725606 | 0.80 | KDM4E (0.31) | — | |
| SCHEMBL7160104 | 0.79 | SLC34A1 (0.32) | — | |
| SCHEMBL6966295 | 0.79 | — | — | |
| SCHEMBL6975701 | 0.79 | SCN9A (0.30) | SCN9A | |
| SCHEMBL4898211 | 0.79 | TDP1 (0.36) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303543-B1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-10-16 | — | — | US | disclosed |
| US-6121201-A | HETEROARYL SUBSTITUTED HALO-PYRAZOLE SUBSTITUTED DIARYL ETHERS OR THIOETHERS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |