SCHEMBL6975701

SCHEMBL6975701

Cn1nc(-c2cc(Oc3sccc3[N+](=O)[O-])c(Cl)cc2F)c(Cl)c1OC(F)F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7936558 0.86 HPGD (0.41)
SCHEMBL7938558 0.85 ATM (0.44)
SCHEMBL7938630 0.83 ALDH1A1 (0.42)
SCHEMBL7891112 0.83 F2 (0.31)
SCHEMBL7749240 0.80 ESPL1 (0.30)
SCHEMBL7935693 0.79 BRD4 (0.37) SCN9A
SCHEMBL7887336 0.77 MAPT (0.34)
SCHEMBL6295368 0.77 PDE10A (0.33)
SCHEMBL6966295 0.76
SCHEMBL9080401 0.75 L3MBTL1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1074551-B1 Phenylpyrazoles with a herbicidal activity ISAGRO RICERCA SRL (IT) 2003-03-26 EP claimed
US-6265351-B1 CONTROLLING WEEDS IN THE AGRONOMIC FIELD. ISAGRO RICERCA S.R.L. (IT) 2001-07-24 US claimed
EP-1074551-A2 Phenylpyrazoles with a herbicidal activity Isagro Ricerca S.r.l. (IT) 2001-02-07 EP claimed
EP-1074551-B1 Phenylpyrazoles with a herbicidal activity ISAGRO RICERCA SRL (IT) 2003-03-26 EP disclosed
US-6265351-B1 CONTROLLING WEEDS IN THE AGRONOMIC FIELD. ISAGRO RICERCA S.R.L. (IT) 2001-07-24 US disclosed
EP-1074551-A2 Phenylpyrazoles with a herbicidal activity Isagro Ricerca S.r.l. (IT) 2001-02-07 EP disclosed