SCHEMBL7935957

SCHEMBL7935957

O=C(O)/C(C1=CC=CC1)=C(\C(=O)O)C1=CC=CC1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17329404 1.00 TSHR (0.32) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL7935963 1.00 TSHR (0.32) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL339906 0.89
SCHEMBL5828929 0.87
SCHEMBL890924 0.80
SCHEMBL28172352 0.78
SCHEMBL28427720 0.78 TSHR (0.42) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL28171680 0.78
SCHEMBL183860 0.77 TSHR (0.31) TSHRMAPK1HSD17B10TDP1
SCHEMBL27285473 0.77 TSHR (0.31) TSHRMAPK1HSD17B10TDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4264754-A HEATING THE DIHYDRODICYCLOPENTADIENYL MONO- OR DIESTER OF FUMATIC OR MALEIC ACID; BLENDS WITH SYNTHETIC RUBBERS; SOLUBILITY; INKS, PAINTS, AND ADHESIVES HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-04-28 US claimed
JP-55083732-A None JP disclosed
JP-55082107-A None JP disclosed
US-10174147-B2 Curable composition and cured product having anti-microbial properties FH MÜNSTER (DE) 2019-01-08 US disclosed
US-9783671-B2 Cross-linked plastic material with an intrinsic antimicrobial effect based on unsaturated polyesters Fachhochschule Münster (DE) 2017-10-10 US disclosed
US-20170210839-A1 Curable Composition and Cured Product Having Anti-Microbial Properties FH MÜNSTER (DE) 2017-07-27 US disclosed
US-20150361259-A1 CROSS-LINKED PLASTIC MATERIAL WITH AN INTRINSIC ANTIMICROBIAL EFFECT BASED ON UNSATURATED POLYESTERS Fachhochschule Münster (DE) 2015-12-17 US disclosed
EP-0946603-B1 METHOD FOR PRODUCING POLYMERS CROSS-LINKABLE BY RADIATION, ACRYLIC- OR METHACRYLIC ACID ESTERS BASF COATINGS AG (DE) 2001-10-31 EP disclosed
EP-0907110-A2 Multi-layer element for the production of lithographic or relief printing plates BASF Drucksysteme GmbH (DE) 1999-04-07 EP disclosed
US-4496688-A UNSATURATED RESIN, UNSATURATED MONOMER, AND DICYCLOPENTADIENE ESTER OF AN UNSATURATED POLYCARBOXYLIC ACID THE DOW CHEMICAL COMPANY (US) 1985-01-29 US disclosed
US-4435530-A Heat resistant resin composition THE DOW CHEMICAL COMPANY (US) 1984-03-06 US disclosed
US-4264754-A HEATING THE DIHYDRODICYCLOPENTADIENYL MONO- OR DIESTER OF FUMATIC OR MALEIC ACID; BLENDS WITH SYNTHETIC RUBBERS; SOLUBILITY; INKS, PAINTS, AND ADHESIVES HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-04-28 US disclosed
US-4264754-A HEATING THE DIHYDRODICYCLOPENTADIENYL MONO- OR DIESTER OF FUMATIC OR MALEIC ACID; BLENDS WITH SYNTHETIC RUBBERS; SOLUBILITY; INKS, PAINTS, AND ADHESIVES HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-04-28 US disclosed
JP-S5583732-A OLIGOMER AND ITS PREPARATION HITACHI CHEM CO LTD 1980-06-24 JP disclosed
JP-S5582107-A ACIDIC OLIGOMER AND THEIR PRODUCTION HITACHI CHEM CO LTD 1980-06-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150361259-A1 CROSS-LINKED PLASTIC MATERIAL WITH AN INTRINSIC ANTIMICROBIAL EFFECT BASED ON UNSATURATED POLYESTERS PUF60, FASN, ALOX5 TSHR 4862/4885MAPK1 2012/4885HSD17B10 599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.