SCHEMBL7936343

SCHEMBL7936343

CC(C)(C)OC(=O)NC1(C(=O)O)C[C@H]1C1CC1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.39
MEN1 O00255 2/20 0.39
MAPK1 P28482 1/20 0.39
BTK Q06187 1/20 0.37
GAA P10253 2/20 0.33
EPHX1 P07099 1/20 0.33
CTSK P43235 3/20 0.32
CTSS P25774 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
ALDH1A1 P00352 1/20 0.31
EPHX2 P34913 1/20 0.31
DGAT1 O75907 1/20 0.31
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3645354 1.00 KMT2A (0.39) KMT2AMEN1MAPK1BTKGAA
SCHEMBL1636480 1.00 KMT2A (0.39) KMT2AMEN1MAPK1BTKGAA
SCHEMBL1635700 1.00 KMT2A (0.39) KMT2AMEN1MAPK1BTKGAA
SCHEMBL15125116 0.88 KMT2A (0.39) KMT2AMEN1MAPK1BTKGAA
SCHEMBL5527908 0.86 MEN1 (0.38) KMT2AMEN1MAPK1BTKGAA
SCHEMBL19388187 0.84 KMT2A (0.37) KMT2AMEN1MAPK1BTKGAA
SCHEMBL15113647 0.84 KMT2A (0.37) KMT2AMEN1MAPK1BTKGAA
SCHEMBL6051013 0.81 KMT2A (0.38) KMT2AMEN1MAPK1BTKGAA
SCHEMBL375218 0.81 KMT2A (0.38) KMT2AMEN1MAPK1BTKGAA
SCHEMBL1433455 0.81 KMT2A (0.38) KMT2AMEN1MAPK1BTKGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100119479-A1 THERAPEUTIC ANTIVIRAL PEPTIDES INTERMUNE, INC. (US) 2010-05-13 US disclosed
US-20100119479-A1 THERAPEUTIC ANTIVIRAL PEPTIDES INTERMUNE, INC. (US) 2010-05-13 US disclosed
WO-2010045266-A1 THERAPEUTIC ANTIVIRAL PEPTIDES INTERMUNE, INC. (US) 2010-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119479-A1 THERAPEUTIC ANTIVIRAL PEPTIDES SARS1, VIP, MAVS KMT2A 4691/4885MEN1 4087/4885MAPK1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.