Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1316252 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4EPOLBKMT2ATDP1 | |
| SCHEMBL28878544 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2ATDP1MAPK1 | |
| SCHEMBL7206146 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2ATDP1MAPK1 | |
| SCHEMBL29291809 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2ATDP1MAPK1 | |
| SCHEMBL21673204 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL5171496 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4881400 | 0.85 | ALDH1A1 (0.55) | ALDH1A1POLBKMT2ATDP1MAPK1 | |
| SCHEMBL27467629 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL1809268 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL7937989 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EPOLBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245810-B1 | ANTITUMOR, ANTICARCINOGENIC AGENTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0617009-B1 | NOVEL AMINO ACID DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5798387-A | IMMUNOMODULATOR AND AN ANTITUMOR AGENT OR HEMATOPOIETIC STEM CELL AMPLIFIER | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-08-25 | — | — | US | disclosed |
| EP-0617009-A1 | NOVEL AMINO ACID DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1994-09-28 | — | — | EP | disclosed |