Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 3/20 | 0.48 |
| ▸ | FNTB | P49356 | 3/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387542 | 0.81 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL1038346 | 0.80 | CYP11B1 (0.41) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7971072 | 0.79 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL9258097 | 0.78 | CYP11B1 (0.68) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL6776413 | 0.77 | CYP11B1 (0.85) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL7475351 | 0.77 | CYP11B1 (0.71) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL7505069 | 0.77 | CYP11B1 (0.74) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL3825172 | 0.77 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1FNTAFNTB | |
| SCHEMBL2961510 | 0.77 | CYP2A6 (0.46) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL7473109 | 0.76 | CYP11B1 (0.70) | CYP11B1CYP11B2CYP19A1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |
| US-5998407-A | ANTICANCER, ANTITUMOR AGENT | MERCK & CO., INC. (US) | 1999-12-07 | — | — | US | disclosed |
| US-5852010-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |