Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 8/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.47 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727937 | 0.89 | SCD (0.67) | SCDDCTPP1 | |
| SCHEMBL10036775 | 0.88 | SCD (0.53) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| Trifluoroacetic Acid SCHEMBL518521 | 0.84 | SCD (0.50) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| SCHEMBL7937701 | 0.84 | HCRTR1 (0.47) | SCDHCRTR1HCRTR2DCTPP1HTR2B | |
| SCHEMBL726265 | 0.76 | SCD (0.67) | SCDDCTPP1 | |
| SCHEMBL2470065 | 0.75 | SCD (0.73) | SCDDCTPP1 | |
| SCHEMBL7936680 | 0.74 | SCD (0.53) | SCDDCTPP1CYP2C9CYP2C19HTR2B | |
| SCHEMBL2466842 | 0.74 | SCD (0.64) | SCDDCTPP1 | |
| SCHEMBL3404868 | 0.74 | SCD (0.59) | SCDDCTPP1 | |
| SCHEMBL2464906 | 0.74 | SCD (0.74) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028761-A1 | 2-HETEROARYL-PYRROLO [3, 4-C]PYRROLE DERIVATIVES AND THE USE THEREOF AS SCD INHIBITORS | SANOFI-AVENTIS (FR) | 2010-03-18 | — | — | WO | disclosed |