Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.47 |
| ▸ | SCD | O00767 | 8/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036776 | 0.86 | P2RX7 (0.44) | SCDHTR2AHTR2CHTR2BDCTPP1 | |
| SCHEMBL7936703 | 0.84 | SCD (0.54) | HCRTR1HCRTR2SCDHTR2BDCTPP1 | |
| SCHEMBL2471047 | 0.76 | SCD (0.59) | SCDDCTPP1 | |
| SCHEMBL2469898 | 0.74 | SCD (0.57) | SCDDCTPP1 | |
| SCHEMBL517783 | 0.74 | SCD (0.52) | SCDHTR2BDCTPP1 | |
| SCHEMBL727937 | 0.74 | SCD (0.67) | SCDDCTPP1 | |
| SCHEMBL7933451 | 0.73 | SCD (0.43) | SCDDCTPP1 | |
| SCHEMBL10036775 | 0.72 | SCD (0.53) | SCDHTR2BDCTPP1 | |
| SCHEMBL518648 | 0.72 | SCD (0.57) | SCDDCTPP1 | |
| Trifluoroacetic Acid SCHEMBL518067 | 0.71 | SCD (0.41) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028761-A1 | 2-HETEROARYL-PYRROLO [3, 4-C]PYRROLE DERIVATIVES AND THE USE THEREOF AS SCD INHIBITORS | SANOFI-AVENTIS (FR) | 2010-03-18 | — | — | WO | disclosed |