Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911615 | 1.00 | TSHR (0.56) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL17097244 | 1.00 | TSHR (0.56) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL11804383 | 1.00 | TSHR (0.56) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL2722719 | 1.00 | TSHR (0.56) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL4903661 | 1.00 | TSHR (0.56) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL868427 | 1.00 | TSHR (0.56) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL2401337 | 0.98 | TSHR (0.54) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL316833 | 0.94 | TSHR (0.53) | TSHRLMNAALDH1A1TP53CYP3A4 | |
| SCHEMBL4912837 | 0.92 | TDP1 (0.58) | TSHRLMNAALDH1A1TDP1POLB | |
| SCHEMBL10936220 | 0.89 | TSHR (0.54) | TSHRLMNAALDH1A1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981758-A | Thermally responsive brush polymers having a copolymer backbone and copolymer arms | 英菲诺姆国际有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-6248805-B1 | THERMAL INK JET PRNTING | HEWLETT-PACKARD COMPANY | 2001-06-19 | — | — | US | disclosed |
| US-3970606-A | N-vinyl lactam interpolymers useful as thickening agents | GAF CORPORATION (US) | 1976-07-20 | — | — | US | disclosed |