SCHEMBL4911615

SCHEMBL4911615

C=C(C(=O)OCCCCCCCCCCCCCCCCCC)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
LMNA P02545 3/20 0.55
ALDH1A1 P00352 3/20 0.55
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAPK1 P28482 1/20 0.53
TDP1 Q9NUW8 2/20 0.50
POLB P06746 2/20 0.49
KDM4E B2RXH2 1/20 0.49
HSD17B10 Q99714 1/20 0.49
PPARG P37231 3/20 0.48
CNR2 P34972 1/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
MAPT P10636 1/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17097244 1.00 TSHR (0.56) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL11804383 1.00 TSHR (0.56) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL2722719 1.00 TSHR (0.56) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL7936965 1.00 TSHR (0.56) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL4903661 1.00 TSHR (0.56) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL868427 1.00 TSHR (0.56) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL2401337 0.98 TSHR (0.54) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL316833 0.94 TSHR (0.53) TSHRLMNAALDH1A1TP53CYP3A4
SCHEMBL4912837 0.92 TDP1 (0.58) TSHRLMNAALDH1A1TDP1POLB
SCHEMBL10936220 0.89 TSHR (0.54) TSHRLMNAALDH1A1TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240247093-A1 MULTI-PITCH TOLERABLE BLOCK COPOLYMERS WITH ENHANCED KINETICS FOR DIRECTED SELF-ASSEMBLY APPLICATIONS MERCK PATENT GMBH (DE) 2024-07-25 US disclosed
EP-4326791-A1 MULTI-PITCH TOLERABLE BLOCK COPOLYMERS WITH ENHANCED KINETICS FOR DIRECTED SELF-ASSEMBLY APPLICATIONS Merck Patent GmbH (DE) 2024-02-28 EP disclosed
CN-117279967-A Multi-spacing block copolymers with enhanced power for directed self-assembly applications 默克专利股份有限公司 2023-12-22 CN disclosed
WO-2022223670-A1 MULTI-PITCH TOLERABLE BLOCK COPOLYMERS WITH ENHANCED KINETICS FOR DIRECTED SELF-ASSEMBLY APPLICATIONS MERCK PATENT GMBH (DE) 2022-10-27 WO disclosed
EP-1791901-B1 STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2018-03-28 EP disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 US disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 US disclosed
US-8569405-B2 Additive mixtures for styrenic polymers BASF SE (DE) 2013-10-29 US disclosed
US-20110046278-A1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (US) 2011-02-24 US disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 US disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 US disclosed
EP-1791901-A2 STABILIZATION OF ORGANIC MATERIALS Ciba SC Holding AG (CH) 2007-06-06 EP disclosed
WO-2006024611-A2 STABILIZATION OF ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269382-A1 Stabilization of Organic Materials LPO, PPOX, HMOX1 TSHR 4809/4885LMNA 1532/4885ALDH1A1 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.