Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935056 | 0.92 | ESR1 (0.68) | ESR1ESR2 | |
| SCHEMBL7937782 | 0.83 | ESR1 (0.66) | ESR1ESR2 | |
| SCHEMBL7929009 | 0.83 | ESR1 (0.74) | ESR1ESR2 | |
| SCHEMBL7928818 | 0.82 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL7934984 | 0.82 | ESR1 (0.72) | ESR1ESR2 | |
| SCHEMBL7928963 | 0.81 | ESR1 (0.69) | ESR1ESR2 | |
| SCHEMBL7937042 | 0.81 | ESR1 (0.71) | ESR1ESR2 | |
| SCHEMBL13389368 | 0.80 | ESR1 (0.77) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL3114483 | 0.79 | ESR1 (0.78) | ESR1ESR2 | |
| SCHEMBL8520074 | 0.79 | ESR1 (0.46) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835868-B1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | LILLY CO ELI (US) | 2001-08-29 | — | — | EP | claimed |
| EP-0835868-A1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | claimed |
| EP-0835868-B1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | LILLY CO ELI (US) | 2001-08-29 | — | — | EP | disclosed |
| US-5929090-A | NOVEL COMPOUNDS FOR TREATING ESTROGEN DEPRIVATION CAUSED BY MENOPAUSE OR OVARIECTOMY; TREATING OSTEOPOROSIS, CARDIOVASCULAR DISEASES, AND ENDOMETRIOSIS | ELI LILLY AND COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0835868-A1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |