SCHEMBL7937231

SCHEMBL7937231

Cc1ccc(-c2ccc(C)c3ccccc23)c2ccccc12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.81
CYP2A6 P11509 4/20 0.61
ALDH1A1 P00352 5/20 0.50
MAPT P10636 3/20 0.48
KDM4E B2RXH2 2/20 0.48
PABPC1 P11940 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 3/20 0.46
ACHE P22303 1/20 0.44
SLC22A12 Q96S37 1/20 0.40
HPGD P15428 4/20 0.40
LMNA P02545 2/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 2/20 0.39
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ATM Q13315 1/20 0.39
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352205 1.00 CYP1A2 (0.81) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL21930041 1.00 CYP1A2 (0.81) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL21929971 1.00 CYP1A2 (0.81) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL29447796 0.90 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL29363045 0.90 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL161370 0.90 CYP1A2 (1.00) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL2380918 0.86 CYP1A2 (0.68) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL260441 0.86 CYP1A2 (0.68) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL29416731 0.86 CYP1A2 (0.68) CYP1A2CYP2A6ALDH1A1MAPTKDM4E
SCHEMBL12556803 0.85 CYP1A2 (0.59) CYP1A2CYP2A6ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675093-B1 Process for preparing 4,4'-dimethyl-1,1'-binaphthyl HOECHST AG (DE) 1998-06-10 EP claimed
US-5522982-A Process for preparing 4,4'-dimethyl-1,1'-binaphthyl HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-04 US claimed
EP-0675093-A1 Process for preparing 4,4'-dimethyl-1,1'-binaphthyl HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP claimed
JP-8041672-A None JP disclosed
JP-8041672-A None JP disclosed
US-20200148541-A1 AN APPROACH TO A BOTTOM-UP SYNTHESIS OF NANOCARBONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2020-05-14 US disclosed
EP-0813517-B1 HYDROGENATION OF UNSATURATED CYCLIC COMPOUNDS CHEMICAL RES & LICENSING CO (US) 2001-11-14 EP disclosed
US-5773670-A CONCURRENT WITH DISTILLATION CATALYTIC DISTILLATION TECHNOLOGIES 1998-06-30 US disclosed
EP-0675093-B1 Process for preparing 4,4'-dimethyl-1,1'-binaphthyl HOECHST AG (DE) 1998-06-10 EP disclosed
EP-0675093-B1 Process for preparing 4,4'-dimethyl-1,1'-binaphthyl HOECHST AG (DE) 1998-06-10 EP disclosed
EP-0813517-A4 HYDROGENATION OF UNSATURATED CYCLIC COMPOUNDS CHEMICAL RES & LICENSIN (US) 1998-04-29 EP disclosed
JP-H0841672-A PREPARATION OF 4,4'-DIMETHYL-1,1'-BINAPHTHYL HOECHST AG 1996-02-13 JP disclosed
JP-H0841672-A PREPARATION OF 4,4'-DIMETHYL-1,1'-BINAPHTHYL HOECHST AG 1996-02-13 JP disclosed
EP-0675093-A1 Process for preparing 4,4'-dimethyl-1,1'-binaphthyl HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
EP-0675093-A1 Process for preparing 4,4'-dimethyl-1,1'-binaphthyl HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
EP-0675093-A1 Process for preparing 4,4'-dimethyl-1,1'-binaphthyl HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
US-4866154-A Aromatic polyester from substituted hydroquinone and biphenyl dicarboxylic acid BAYER AKTIENGESELLSCHAFT (DE) 1989-09-12 US disclosed
EP-0303891-A2 Aromatic polyesters, process for their preparation and their use in the preparation of molecularly reinforced polymers BAYER AG (DE) 1989-02-22 EP disclosed
US-4482438-A ELECTROLYSIS ANODIC OXIDATION, REDOX SYSTEMS/ ELECTROLYSIS, ANODIC OXIDATION, REDOX SYSTEMS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-11-13 US disclosed
EP-0102762-A2 Method of performing a chemical reaction NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200148541-A1 AN APPROACH TO A BOTTOM-UP SYNTHESIS OF NANOCARBONS TYMS, NCL, PFAS CYP1A2 711/4885CYP2A6 1259/4885ALDH1A1 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.