Benzene

Benzene

SCHEMBL7937270

c1ccc2c[nH]cc2c1.c1ccc2c[nH]cc2c1.c1ccc2c[nH]cc2c1.c1ccccc1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.47
ALOX12 P18054 1/20 0.47
ALDH1A1 P00352 6/20 0.37
HSD17B10 Q99714 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
TSHR P16473 2/20 0.37
MAPT P10636 3/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
DAO P14920 2/20 0.36
SRD5A2 P31213 1/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TRPA1 O75762 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
ITGB2 P05107 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60689 0.96
SCHEMBL30253511 0.93 CYP2A6 (0.47) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
SCHEMBL27384288 0.93
SCHEMBL30505849 0.93 CYP2A6 (0.47) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
SCHEMBL29649306 0.93 CYP2A6 (0.47) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
SCHEMBL28644224 0.93 CYP2A6 (0.47) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Hydrochloric Acid SCHEMBL2434708 0.93 CYP2A6 (0.47) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Biphenyl SCHEMBL27758183 0.91 ALDH1A1 (0.53) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Hydrochloric Acid SCHEMBL27365162 0.90 CYP2A6 (0.44) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Fluoride SCHEMBL30505845 0.90 CYP2A6 (0.44) CYP2A6ALOX12ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6294635-B1 CONTAINING PALLADIUM COMPOUND HEAT STABILIZER; HEAT RESISTANCE WACKER-CHEMIE GMBH (DE) 2001-09-25 US disclosed