Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 6/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | BAX | Q07812 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938157 | 0.93 | ESR2 (0.50) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL7938528 | 0.86 | ESR2 (0.52) | MEN1KMT2AESR1ESR2KDM4E | |
| SCHEMBL7929131 | 0.81 | ESR1 (0.56) | MEN1KMT2AESR1ESR2KDM4E | |
| SCHEMBL7938025 | 0.81 | NR1H2 (0.56) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL249169 | 0.80 | ESR2 (1.00) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL10712854 | 0.80 | MEN1 (0.34) | MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL18198 | 0.80 | ESR2 (1.00) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL3175106 | 0.80 | ESR2 (1.00) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL7811939 | 0.80 | ESR2 (1.00) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL7937266 | 0.79 | ESR2 (0.61) | MEN1KMT2AESR1ESR2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |