Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796635 | 0.83 | RAB9A (0.50) | RAB9ANPC1HTR2BHTR7HTR2C | |
| SCHEMBL3704663 | 0.83 | RAB9A (0.50) | RAB9ANPC1HTR2BHTR7HTR2C | |
| SCHEMBL1608310 | 0.83 | NPC1 (0.50) | RAB9ANPC1HTR2BHTR7HTR2C | |
| SCHEMBL3491774 | 0.81 | NPC1 (0.59) | RAB9ANPC1HTR2BHTR7HTR2C | |
| Fluorene SCHEMBL28131122 | 0.80 | RAB9A (0.58) | RAB9ANPC1HTR2BHTR7HTR2C | |
| Ammonia Solution, Strong SCHEMBL27320939 | 0.80 | NPC1 (0.58) | RAB9ANPC1HTR2BHTR7HTR2C | |
| SCHEMBL3720118 | 0.79 | HSP90AA1 (0.50) | RAB9ANPC1HTR2BHTR7HTR2C | |
| SCHEMBL31158183 | 0.79 | HSP90AA1 (0.50) | RAB9ANPC1HTR2BHTR7HTR2C | |
| SCHEMBL30647966 | 0.77 | HTR2B (0.51) | RAB9ANPC1HTR2BHTR7HTR2C | |
| SCHEMBL31301114 | 0.77 | NPC1 (0.45) | RAB9ANPC1HTR2BHTR7HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0666267-B1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-04-18 | — | — | EP | disclosed |
| CN-1060176-C | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 2001-01-03 | — | — | CN | disclosed |
| US-5571880-A | CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS | PHILLIPS PETROLEUM COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| CN-1109472-A | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM CO (US) | 1995-10-04 | — | — | CN | disclosed |
| EP-0666267-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-08-09 | — | — | EP | disclosed |
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |