Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094713 | 0.90 | SLC29A1 (0.42) | SLC29A1HTTALDH1A1POLBKHK | |
| Hydrochloric Acid SCHEMBL16094548 | 0.89 | SLC29A1 (0.41) | SLC29A1HTTALDH1A1POLBKHK | |
| SCHEMBL16094412 | 0.87 | SLC29A1 (0.42) | SLC29A1HTTALDH1A1POLBKHK | |
| SCHEMBL16094710 | 0.86 | SLC29A1 (0.65) | SLC29A1MEN1LMNAKMT2AAPP | |
| Hydrochloric Acid SCHEMBL17494522 | 0.84 | SLC29A1 (0.62) | SLC29A1MEN1LMNAKMT2AAPP | |
| SCHEMBL7937484 | 0.83 | SLC29A1 (0.39) | SLC29A1POLBKHKLMNAAPP | |
| SCHEMBL16094226 | 0.79 | SLC29A1 (0.77) | SLC29A1APPBCHEACHECA1 | |
| SCHEMBL16094399 | 0.78 | SLC29A1 (0.56) | SLC29A1POLBMEN1LMNAKMT2A | |
| SCHEMBL16094511 | 0.78 | SLC29A1 (0.56) | SLC29A1MEN1LMNAKMT2AAPP | |
| Hydrochloric Acid SCHEMBL16094767 | 0.77 | SLC29A1 (0.75) | SLC29A1APPBCHEACHECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |