Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.35 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937489 | 0.90 | MAP4K4 (0.37) | SLC29A1MAP4K4KDM4EFFAR2BCHE | |
| SCHEMBL18806440 | 0.84 | LMNA (0.50) | SLC29A1LMNAGAAPOLBAPP | |
| SCHEMBL7937472 | 0.83 | SLC29A1 (0.51) | SLC29A1LMNAPOLBAPPBCHE | |
| SCHEMBL7930938 | 0.81 | LMNA (0.41) | MAP4K4LMNAKDM4EFFAR2ADORA1 | |
| SCHEMBL16094713 | 0.77 | SLC29A1 (0.42) | SLC29A1LMNAPOLBAPPBCHE | |
| Hydrochloric Acid SCHEMBL16094548 | 0.76 | SLC29A1 (0.41) | SLC29A1LMNAPOLBAPPBCHE | |
| SCHEMBL17494542 | 0.74 | LMNA (0.61) | SLC29A1LMNAGAAL3MBTL1CYP1A2 | |
| SCHEMBL16094412 | 0.73 | SLC29A1 (0.42) | SLC29A1LMNAPOLBAPPBCHE | |
| SCHEMBL16094399 | 0.73 | SLC29A1 (0.56) | SLC29A1LMNAGAAPOLBAPP | |
| SCHEMBL16094511 | 0.73 | SLC29A1 (0.56) | SLC29A1LMNAAPPBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |