Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 19/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632629 | 0.91 | MTOR (0.72) | MTORPIK3CA | |
| SCHEMBL7946426 | 0.88 | MTOR (0.69) | MTORPIK3CA | |
| SCHEMBL7945048 | 0.88 | MTOR (0.69) | MTORPIK3CA | |
| SCHEMBL3722216 | 0.87 | MTOR (0.82) | MTORPIK3CAPIK3CG | |
| Hydrochloric Acid SCHEMBL15189895 | 0.86 | MTOR (0.80) | MTORPIK3CAPIK3CG | |
| SCHEMBL1834122 | 0.85 | MTOR (0.58) | MTORPIK3CA | |
| SCHEMBL1834119 | 0.85 | MTOR (0.58) | MTORPIK3CA | |
| SCHEMBL412940 | 0.84 | MTOR (1.00) | MTORPIK3CAPIK3CG | |
| Hydrochloric Acid SCHEMBL1831687 | 0.83 | MTOR (0.98) | MTORPIK3CAPIK3CG | |
| SCHEMBL411859 | 0.83 | MTOR (0.60) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014939-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2010-02-04 | — | — | WO | disclosed |